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Exosomes: the new pro-firm generation

EXO...WHAT? EXOSOMES

the skin “whatsapp” to the rescue

If you have ever thought that your skin “doesn't know” what you apply to it, we have good news: it does. And a lot. In large part, thanks to its exosomes. Small, sophisticated and absolutely key in cosmetic science more advanced. Keep reading, because this interests you.


What exactly are exosomes?

Imagine ultralight microbubbles traveling across your skin carrying valuable information. Those are exosomes: microscopic vesicles that cells release to communicate with each other. Inside they transport proteins, lipids and genetic material that tell other cells what to do and when to do it, activating some natural skin mechanisms, such as those that improve firmness.

Exosomes are your skin's internal messaging system.  

How do exosomes work in cosmetics?

Exosomes allow cells to coordinate key processes such as regeneration or repair. But here is an important nuance: not all cosmetics based In this science they work the same.

Some incorporate external exosomes, of biomimetic or plant origin. Instead, Essential Shock (R)Evolution products include an active ingredient that helps activate intelligently the skin's own mechanisms, respecting its biology and enhancing its natural response capacity.

Exosomes, menopause and skin

During menopause, hormonal changes slow down many skin processes: cell renewal It slows down, collagen plummets and the skin loses density and elasticity.

This is where exosomes take center stage, since they contribute to improving functions that the skin did “automatically” before this stage.

Pro-Exo Protein System: a boost for your skin

At Essential Shock (R)Evolution we do not add external exosomes. We include Pro-Exo Protein System™, with an active ingredient that enhances your own exosomes from your skin.

In vitro efficacy studies show that this system interacts with the skin microbiome and optimizes cellular communication.

This advanced signage helps:

  • ✓ Strengthen the union between dermis and epidermis
  • ✓ Strengthen the extracellular matrix
  • ✓ Protect against processes that weaken firmness
  • ✓ Stimulate collagen production (types I, III and IV)

What do exosomes have to do with collagen and elastin? 

A lot. Very much.

Exosomes participate in the activation of fibroblasts, the cells responsible for producing collagen and elastin. When the “work” signal comes to them clearly and on time, they can produce these structural fibers more efficiently.

Translated in the mirror:

  • ★ More firmness
  • ★ More elasticity
  • ★ Better density
  • ★ And skin that looks stronger and more resistant

Pro-longevity cosmetics

At Natura Bissé we understand skin care as a long-term strategy. That's why we formulate advanced cosmetics to support your biological intelligence, helping you function better today and stay beautiful over time.

The science of longevity points to cellular communication as one of the pillars for age well and, with this philosophy in mind, we design cosmetics like those from Essential Shock (R)Evolution, with the pro-exosome complex Pro-Exo Protein System™, promote the production of your own exosomes, your skin's cellular messengers, which help preserve its firmness and beauty.

Discover our pro-exosome trio

Scientific sources

  • ﹒Raposo, G. & Stoorvogel, W. Extracellular vesicles: exosomes, microvesicles, and friends. Journal of Cell Biology, 2013.
  • ﹒Kalluri, R. & LeBleu, V.S. The biology, function, and biomedical applications of exosomes. Science, 2020.
  • ﹒Liang, C., Yi, Y., Li, J., Aghayants, S., Chen, X., Cao, W., & Zhang, Q. (2025). Unveiling exosomes in combating skin aging: Insights into resources, mechanisms and challenges. Stem Cell Research & Therapy, 16, 474.
  • ﹒Sreeraj, H., AnuKiruthika, R., Tamilselvi, K. S., & Subha, D. (2024). Exosomes for skin treatment: Therapeutic and cosmetic applications. Nanotechnology for Medicine, 100048.